Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL133561

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
CN(CCCCCCCCN(C)C(=O)CCCCCNCC(=O)N1c2ccccc2C(=O)Nc2cccnc21)C(=O)CCCCCNCC(=O)N1c2ccccc2C(=O)Nc2cccnc21

Basic Information

ChEMBL ID CHEMBL133561
Phase Preclinical
Structure Type MOL
InChI Key JCGWIDAZMHRIEY-UHFFFAOYSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

901.1
MW (Da)
7.20
ALogP
10
HBA
4
HBD
189.3
PSA (Ų)
0.05
QED
2
Ro5 Violations
25
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C50H64N10O6
MW 901.13
Aromatic Rings 4
Heavy Atoms 66
NP-Likeness -0.39

Activity Summary

Kd 2 meas. best 9.3

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Muscarinic acetylcholine receptor M2
CHEMBL211
Kd 9.3 9.3 0.5 1
Muscarinic acetylcholine receptor M3
CHEMBL5498
Kd 7.14 7.14 72.4 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
9767650 10.1021/jm981038d Muscarinic acetylcholine receptor M2 1
9767650 10.1021/jm981038d Muscarinic acetylcholine receptor M3 1

Data from ChEMBL 36 via Core Engine