Muscarinic acetylcholine receptor M3 · SINGLE PROTEIN · Cavia porcellus
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As of 2026-09-13Protein identity stays anchored to UniProt Q8VH26. Use UniProt Q8VH26 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8VH26 as the stable identity anchor, then attach disease evidence before program review.
Muscarinic acetylcholine receptor
Review this target as Muscarinic acetylcholine receptor M3, mapped to UniProt Q8VH26. ChEMBL maps the protein component as Muscarinic acetylcholine receptor. Sequence length is 587 aa.
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This review treats Muscarinic acetylcholine receptor M3 as ChEMBL target CHEMBL5498, mapped to UniProt Q8VH26. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Muscarinic acetylcholine receptor M3 |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | Q8VH26 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Muscarinic acetylcholine receptor |
| UniProt Accession | Q8VH26 |
| Component Type | Protein |
| Sequence Length | 587 aa |
Muscarinic acetylcholine receptor
Review this target as Muscarinic acetylcholine receptor M3, mapped to UniProt Q8VH26. ChEMBL maps the protein component as Muscarinic acetylcholine receptor. Sequence length is 587 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3087240 | 10.7 | Kd | 0.01995 | Preclinical |
| CHEMBL92421 | 10.35 | EC50 | 0.045 | Preclinical |
| CHEMBL3087368 | 10.1 | Kd | 0.07943 | Preclinical |
| CHEMBL3087236 | 10.1 | Kd | 0.07943 | Preclinical |
| CHEMBL21905 | 10.05 | Ki | 0.09 | Preclinical |
| CHEMBL3087230 | 10.0 | Kd | 0.1 | Preclinical |
| CHEMBL5184455 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL21812 | 9.92 | Ki | 0.12 | Preclinical |
| CHEMBL3087229 | 9.9 | Kd | 0.1259 | Preclinical |
| CHEMBL3087369 | 9.9 | Kd | 0.1259 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 65 | 123 | 6.7 |
| assay format | 42 | 41 | 7.4 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 36 | 75 | 6.9 |
| single protein format | 13 | 64 | 7.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 1 | 0 | — |