Compound Detail
CHEMBL1352344
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Basic Information
| ChEMBL ID | CHEMBL1352344 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WPDRUGWTCLPNBA-JOBJLJCHSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
269.4
MW (Da)
4.08
ALogP
2
HBA
0
HBD
20.3
PSA (Ų)
0.77
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 6.29
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Ion channel NompC CHEMBL1293245 | EC50 | 6.29 | 6.29 | 507.0 | 1 |
| Mucolipin-3 CHEMBL1293243 | EC50 | 5.72 | 5.72 | 1900.0 | 1 |
| Unchecked CHEMBL612545 | EC50 | 5.03 | 5.03 | 9450.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Ion channel NompC | EC50 | = | 507.0 | nM | 6.29 | PUBCHEM_BIOASSAY: Dose response cell-based high-throughput screening assay for a... | - |
| Mucolipin-3 | EC50 | = | 1900.0 | nM | 5.72 | PUBCHEM_BIOASSAY: Fluorescence counterscreen assay for TRPN1 agonists: dose resp... | - |
| Unchecked | EC50 | = | 9450.0 | nM | 5.03 | PUBCHEM_BIOASSAY: Counterscreen for Fluorescence in GFP-Spectra Wavelengths Caus... | - |
Data from ChEMBL 36 via Core Engine