Compound Detail
CHEMBL1362864
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1362864 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DGQXIDAJSBKRMJ-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
255.3
MW (Da)
4.12
ALogP
3
HBA
0
HBD
20.3
PSA (Ų)
0.71
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NADPH oxidase 1 CHEMBL1287628 | IC50 | 6.0 | 5.815 | 1000.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NADPH oxidase 1 | IC50 | = | 1000.0 | nM | 6.0 | PUBCHEM_BIOASSAY: Luminescence-based cell-based dose response assay to identify ... | - |
| NADPH oxidase 1 | IC50 | = | 2360.0 | nM | 5.63 | PUBCHEM_BIOASSAY: Late-stage luminescence-based cell-based dose response assay t... | - |
Data from ChEMBL 36 via Core Engine