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Compound Detail

CHEMBL1365411

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CCCNC(=O)c1ccc2c(O)c(O)c(-c3ccc(C)cc3)nc2c1

Basic Information

ChEMBL ID CHEMBL1365411
Phase Preclinical
Structure Type MOL
InChI Key XXPMVUNCOJGLHG-UHFFFAOYSA-N
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

336.4
MW (Da)
3.76
ALogP
4
HBA
3
HBD
82.5
PSA (Ų)
0.68
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C20H20N2O3
MW 336.39
Aromatic Rings 3
Heavy Atoms 25
NP-Likeness -0.88

Activity Summary

EC50 2 meas. best 5.05

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
EC50 5.05 5.03 8863.0 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine