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Compound Detail

CHEMBL1367952

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O=C(O)c1ccccc1N=Nc1c(O)[nH]c2ccc([N+](=O)[O-])cc12

Basic Information

ChEMBL ID CHEMBL1367952
Phase Preclinical
Structure Type MOL
InChI Key VDWIKAWAMKZYSW-UHFFFAOYSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

326.3
MW (Da)
3.90
ALogP
6
HBA
3
HBD
141.2
PSA (Ų)
0.38
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C15H10N4O5
MW 326.27
Aromatic Rings 3
Heavy Atoms 24
NP-Likeness -0.97

Activity Summary

IC50 2 meas. best 5.0

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 5.0 5.0 10090.0 1
Envelope glycoprotein gp160
CHEMBL1293311
IC50 4.63 4.63 23300.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine