Compound Detail
CHEMBL137420
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL137420 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FVMSCSAZMNXMPH-MRXNPFEDSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
318.2
MW (Da)
3.73
ALogP
2
HBA
1
HBD
23.5
PSA (Ų)
0.87
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.08
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(1A) dopamine receptor CHEMBL265 | Ki | 8.08 | 8.08 | 8.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(1A) dopamine receptor | Ki | = | 8.318 | nM | 8.08 | Binding affinity against dopamine receptor D1 | 7996543 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7996543 | 10.1021/jm00051a008 | D(1A) dopamine receptor | 3 |
Data from ChEMBL 36 via Core Engine