Compound Detail
CHEMBL1391235
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Basic Information
| ChEMBL ID | CHEMBL1391235 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FKCYENFBFZUSDP-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
290.3
MW (Da)
1.93
ALogP
6
HBA
3
HBD
96.2
PSA (Ų)
0.74
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.53
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Female germline-specific tumor suppressor gld-1 CHEMBL1293302 | IC50 | 5.53 | 5.53 | 2957.0 | 1 |
| Protein Rev CHEMBL1293282 | IC50 | 4.79 | 4.79 | 16241.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Female germline-specific tumor suppressor gld-1 | IC50 | = | 2957.0 | nM | 5.53 | PUBCHEM_BIOASSAY: Fluorescence polarization-based biochemical high throughput do... | - |
| Protein Rev | IC50 | = | 16241.0 | nM | 4.79 | PUBCHEM_BIOASSAY: Counterscreen for inhibitors of gld-1: Fluorescence polarizati... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 26711143 | 10.1016/j.bmcl.2015.12.005 | Human immunodeficiency virus 1 | 1 |
Data from ChEMBL 36 via Core Engine