Compound Detail
CHEMBL139630
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CC(=O)O[C@@H]1C2CC[C@H]3C4CC=C([C@H](C)N(C)C)[C@@]4(C)CC[C@@H]3[C@@]2(C)CC[C@@H]1NC(=O)C=C(C)C
Basic Information
| ChEMBL ID | CHEMBL139630 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SYWAOYCXRQDRLP-VLNZMSLLSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
484.7
MW (Da)
5.51
ALogP
4
HBA
1
HBD
58.6
PSA (Ų)
0.32
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.28
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Acetylcholinesterase CHEMBL220 | IC50 | 5.28 | 5.28 | 5248.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Acetylcholinesterase | IC50 | = | 5248.07 | nM | 5.28 | Compound was tested for the in silico inhibition of acetylcholinesterase | 14643329 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 14643329 | 10.1016/j.bmcl.2003.09.034 | Acetylcholinesterase | 1 |
Data from ChEMBL 36 via Core Engine