Compound Detail
CHEMBL14021
PROPIONIC ACID 🧪 Phase II
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🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL14021 |
| Name | PROPIONIC ACID |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | XBDQKXXYIPTUBI-UHFFFAOYSA-N |
1
Targets
12
Activities
3
Assay Types
0
PK Parameters
20
Publications
12
Known Names
Molecular Properties
74.1
MW (Da)
0.48
ALogP
1
HBA
1
HBD
37.3
PSA (Ų)
0.49
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Activity Summary
EC50 6 meas. best 4.97
Ki 4 meas.
IC50 2 meas.
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Free fatty acid receptor 3 CHEMBL5201 | EC50 | 4.97 | 4.94 | 10715.2 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Free fatty acid receptor 3 | EC50 | = | 10715.19 | nM | 4.97 | Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 ... | 32141297 |
| Free fatty acid receptor 3 | EC50 | = | 11748.98 | nM | 4.93 | Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 ... | 32141297 |
| Free fatty acid receptor 3 | EC50 | = | 12000.0 | nM | 4.92 | Agonist activity at human GPCR41 transfected in HEK293 cells assessed as [35S]GT... | 28745893 |
Literature References
Data from ChEMBL 36 via Core Engine