Compound Detail
CHEMBL140580
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Basic Information
| ChEMBL ID | CHEMBL140580 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KDWBVFKRIZXKBI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
417.9
MW (Da)
5.61
ALogP
4
HBA
2
HBD
77.2
PSA (Ų)
0.44
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.43
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Nociceptin receptor CHEMBL2014 | Ki | 7.43 | 7.43 | 37.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Nociceptin receptor | Ki | = | 37.3 | nM | 7.43 | Ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like ... | 11101358 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11101358 | 10.1021/jm0002073 | Nociceptin receptor | 1 |
Data from ChEMBL 36 via Core Engine