Compound Detail
CHEMBL141966
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Basic Information
| ChEMBL ID | CHEMBL141966 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JKXLRLDPSLZEDD-UHFFFAOYSA-N |
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
326.5
MW (Da)
3.08
ALogP
5
HBA
1
HBD
64.1
PSA (Ų)
0.82
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 4 meas. best 8.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HeLa CHEMBL399 | EC50 | 8.52 | 7.5525 | 3.0 | 4 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HeLa | EC50 | = | 3.0 | nM | 8.52 | Compound was tested for its inhibition of HIV-1 induced focus formation in MAGI-... | 10579814 |
| HeLa | EC50 | = | 3.0 | nM | 8.52 | Compound was tested for its inhibition of HIV-1 induced focus formation in MAGI-... | 10579814 |
| HeLa | EC50 | = | 250.0 | nM | 6.6 | Compound was tested for its inhibition of HIV-1 induced focus formation in MAGI-... | 10579814 |
| HeLa | EC50 | = | 270.0 | nM | 6.57 | Compound was tested for its inhibition of HIV-1 induced focus formation in MAGI-... | 10579814 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10579814 | 10.1021/jm990192c | HeLa | 5 |
Data from ChEMBL 36 via Core Engine