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Compound Detail

CHEMBL1422601

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Cc1ccc(-c2nc(SCC(=O)Nc3ccccc3OC(F)F)c3c(C)c(C(=O)O)sc3n2)cc1

Basic Information

ChEMBL ID CHEMBL1422601
Phase Preclinical
Structure Type MOL
InChI Key PASXOQMBSRXXQZ-UHFFFAOYSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

515.6
MW (Da)
6.01
ALogP
7
HBA
2
HBD
101.4
PSA (Ų)
0.22
QED
2
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C24H19F2N3O4S2
MW 515.56
Aromatic Rings 4
Heavy Atoms 35
NP-Likeness -2.32

Activity Summary

IC50 2 meas. best 4.82

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Envelope glycoprotein gp160
CHEMBL1293311
IC50 4.82 4.82 15100.0 1
Unchecked
CHEMBL612545
IC50 4.73 4.73 18810.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine