Compound Detail
CHEMBL1424929
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Basic Information
| ChEMBL ID | CHEMBL1424929 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RRDSAZVIDPLSSF-CXUHLZMHSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
428.3
MW (Da)
6.45
ALogP
4
HBA
1
HBD
65.8
PSA (Ų)
0.49
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.27
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| G-protein coupled receptor 35 CHEMBL1293267 | IC50 | 6.27 | 6.27 | 533.8 | 1 |
| Envelope glycoprotein gp160 CHEMBL1293311 | IC50 | 5.69 | 5.69 | 2040.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| G-protein coupled receptor 35 | IC50 | = | 533.78 | nM | 6.27 | PUBCHEM_BIOASSAY: Image-Based HTS for Selective Antagonists of GPR35. High conte... | - |
| Envelope glycoprotein gp160 | IC50 | = | 2040.0 | nM | 5.69 | PUBCHEM_BIOASSAY: uHTS fluorescence assay for the identification of Human Immuno... | - |
Data from ChEMBL 36 via Core Engine