Compound Detail
CHEMBL142872
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL142872 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CCDMTBWWYPHEAW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
273.2
MW (Da)
1.34
ALogP
7
HBA
3
HBD
138.1
PSA (Ų)
0.47
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor ionotropic, AMPA CHEMBL2093871 | Ki | 6.16 | 6.16 | 690.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor ionotropic, AMPA | Ki | = | 690.0 | nM | 6.16 | Binding affinity against AMPA receptor in rat brain membrane using [3H]-AMPA as ... | 8120865 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8120865 | 10.1021/jm00030a006 | Glutamate receptor ionotropic, AMPA | 1 |
Data from ChEMBL 36 via Core Engine