Compound Detail
CHEMBL143357
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL143357 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HPWZLKOTRHSKTD-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
510.7
MW (Da)
5.92
ALogP
5
HBA
2
HBD
101.7
PSA (Ų)
0.32
QED
2
Ro5 Violations
13
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Homo sapiens CHEMBL372 | IC50 | 8.52 | 8.41 | 3.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Homo sapiens | IC50 | = | 3.0 | nM | 8.52 | Compound was evaluated for the ability to inhibit arachidonic acid induced plate... | - |
| Homo sapiens | IC50 | = | 5.0 | nM | 8.3 | Compound was evaluated for the ability to inhibit U-46649 induced platelet aggre... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(01)81106-9 | Homo sapiens | 2 |
Data from ChEMBL 36 via Core Engine