Assay Detail
Functional
CHEMBL698015
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for the ability to inhibit U-46649 induced platelet aggregation (U-IPA) in human platelet rich plasma.
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Plasma |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Interphenylene 7-oxabicyclo[2.2.1]heptanes. SQ33,961: a new potent, long-acting thromboxane antagonist
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 7.89 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL143357 | — | — | 1 | 8.30 |
| CHEMBL31765 | — | — | 1 | 8.22 |
| CHEMBL418585 | — | — | 1 | 8.22 |
| CHEMBL95872 | — | — | 1 | 7.92 |
| CHEMBL30615 | — | — | 1 | 7.89 |
| CHEMBL30743 | — | — | 1 | 7.89 |
| CHEMBL31334 | — | — | 1 | 7.60 |
| CHEMBL33621 | — | — | 1 | 7.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL143357 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL31765 | — | IC50 | = | 6.0 | nM | 8.22 |
| CHEMBL418585 | — | IC50 | = | 6.0 | nM | 8.22 |
| CHEMBL95872 | — | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL30615 | — | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL30743 | — | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL31334 | — | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL33621 | — | IC50 | = | 81.0 | nM | 7.09 |