Compound Detail
CHEMBL143493
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Basic Information
| ChEMBL ID | CHEMBL143493 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GZRRKQOVRJEUJB-UHFFFAOYSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
173.3
MW (Da)
2.21
ALogP
2
HBA
2
HBD
26.0
PSA (Ų)
0.63
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.35
Ki 1 meas.
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Aminopeptidase N CHEMBL2590 | IC50 | 7.35 | 7.35 | 45.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Aminopeptidase N | IC50 | = | 45.0 | nM | 7.35 | Compound was tested for inhibitory potency against aminopeptidase N from hog kid... | 1348542 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1348542 | 10.1021/jm00085a013 | Aminopeptidase N | 1 |
| 14561084 | 10.1021/jm0300680 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine