Compound Detail
CHEMBL144599
IODOHYDRIN PYROPHOSPHATE Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL144599 |
| Name | IODOHYDRIN PYROPHOSPHATE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IOIWLRQDYYHXOR-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
390.0
MW (Da)
0.79
ALogP
5
HBA
4
HBD
133.5
PSA (Ų)
0.28
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 8.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 8.92 | 8.72 | 1.2 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 1.2 | nM | 8.92 | Effective concentration to activate gammadelta T cells | 12383012 |
| Unchecked | EC50 | = | 3.0 | nM | 8.52 | Effective concentration range of compound was determined in stimulating Vgamma9 ... | 12657258 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12383012 | 10.1021/jm020224n | Unchecked | 1 |
| 12657258 | 10.1016/s0960-894x(03)00138-0 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine