Compound Detail
CHEMBL1468531
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Basic Information
| ChEMBL ID | CHEMBL1468531 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FSANKFXSCSQHPY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
310.4
MW (Da)
3.00
ALogP
5
HBA
1
HBD
59.8
PSA (Ų)
0.74
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 2.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human immunodeficiency virus type 1 reverse transcriptase CHEMBL247 | Kd | 2.77 | 2.77 | 1700000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus type 1 reverse transcriptase | Kd | = | 1700000.0 | nM | 2.77 | Binding affinity to HIV1 reverse transcriptase by surface plasmon resonance base... | 21207958 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21207958 | 10.1021/jm101052g | Human immunodeficiency virus type 1 reverse transcriptase | 1 |
Data from ChEMBL 36 via Core Engine