Compound Detail
CHEMBL1469043
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Basic Information
| ChEMBL ID | CHEMBL1469043 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CKRIVDIJIWXCAG-MDWZMJQESA-N |
2
Targets
3
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
369.3
MW (Da)
2.16
ALogP
6
HBA
2
HBD
122.0
PSA (Ų)
0.36
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 4.44
IC50 1 meas. best 5.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.17 | 5.17 | 6780.0 | 1 |
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 4.44 | 4.44 | 36176.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 6780.0 | nM | 5.17 | PUBCHEM_BIOASSAY: A biochemical assay using the ADP-Hunter methodology, purified... | - |
| Zinc finger protein mex-5 | EC50 | = | 36176.0 | nM | 4.44 | PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Iden... | - |
Data from ChEMBL 36 via Core Engine