Compound Detail
CHEMBL14722
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Basic Information
| ChEMBL ID | CHEMBL14722 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CPAGZVLINCPJEH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
125.2
MW (Da)
-0.08
ALogP
3
HBA
1
HBD
43.8
PSA (Ų)
0.60
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 9.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histamine H3 receptor CHEMBL4124 | Ki | 9.0 | 9.0 | 1.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histamine H3 receptor | Ki | = | 1.0 | nM | 9.0 | Inhibition of [3H]- N-alpha-methylhistamine from histamine H3 receptor | 9871722 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.6019/CHEMBL3988442 | Unchecked | 3 |
| - | 10.6019/CHEMBL4513160 | Pseudomonas aeruginosa | 2 |
| 9871722 | 10.1016/s0960-894x(98)00181-4 | Histamine H3 receptor | 1 |
| 9871722 | 10.1016/s0960-894x(98)00181-4 | Cavia porcellus | 1 |
| - | 10.6019/CHEMBL4513160 | Acinetobacter baumannii | 1 |
Data from ChEMBL 36 via Core Engine