Compound Detail
CHEMBL1486938
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Basic Information
| ChEMBL ID | CHEMBL1486938 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZWBYTNOGSNZJMX-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
486.4
MW (Da)
5.46
ALogP
5
HBA
0
HBD
55.8
PSA (Ų)
0.50
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.06
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Runt-related transcription factor 1/Core-binding factor subunit beta CHEMBL2093862 | IC50 | 6.06 | 5.22 | 865.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Runt-related transcription factor 1/Core-binding factor subunit beta | IC50 | = | 865.0 | nM | 6.06 | PUBCHEM_BIOASSAY: uHTS identification of compounds inhibiting the binding betwee... | - |
| Runt-related transcription factor 1/Core-binding factor subunit beta | IC50 | = | 41200.0 | nM | 4.38 | PUBCHEM_BIOASSAY: Identification of compounds inhibiting the binding between the... | - |
Data from ChEMBL 36 via Core Engine