Compound Detail
CHEMBL149539
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Basic Information
| ChEMBL ID | CHEMBL149539 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OMFGOOBBWMNOHG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
482.5
MW (Da)
5.64
ALogP
8
HBA
1
HBD
103.3
PSA (Ų)
0.29
QED
1
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.05 | 6.05 | 900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 900.0 | nM | 6.05 | Inhibition of specific binding of [125I]angiotensin II (0.2 nM) to angiotensin I... | 8978851 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8978851 | 10.1021/jm960547h | Rattus norvegicus | 2 |
| 8978851 | 10.1021/jm960547h | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine