Compound Detail
CHEMBL1500987
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Basic Information
| ChEMBL ID | CHEMBL1500987 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OKPRCZZOBQAZOL-YBEGLDIGSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
368.4
MW (Da)
3.06
ALogP
6
HBA
0
HBD
102.9
PSA (Ų)
0.35
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Perilipin-1/ABHD5 CHEMBL3883313 | IC50 | 5.68 | 5.68 | 2068.0 | 1 |
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5/Perilipin-5 CHEMBL3885501 | IC50 | 5.64 | 5.64 | 2269.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Perilipin-1/ABHD5 | IC50 | = | 2068.0 | nM | 5.68 | PUBCHEM_BIOASSAY: Luminescence-based biochemical high throughput dose response a... | - |
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5/Perilipin-5 | IC50 | = | 2269.0 | nM | 5.64 | PUBCHEM_BIOASSAY: Luminescence-based biochemical high throughput dose response a... | - |
Data from ChEMBL 36 via Core Engine