Perilipin-1/ABHD5 · PROTEIN-PROTEIN INTERACTION · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q8WTS1. Use UniProt Q8WTS1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8WTS1 as the stable identity anchor, then attach disease evidence before program review.
1-acylglycerol-3-phosphate O-acyltransferase ABHD5
Review this target as Perilipin-1/ABHD5, mapped to UniProt Q8WTS1. ChEMBL maps the protein component as 1-acylglycerol-3-phosphate O-acyltransferase ABHD5. Sequence length is 349 aa.
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This review treats Perilipin-1/ABHD5 as ChEMBL target CHEMBL3883313, mapped to UniProt Q8WTS1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Perilipin-1/ABHD5 |
| Target Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
| UniProt | Q8WTS1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 |
| UniProt Accession | Q8WTS1 |
| Component Type | Protein |
| Sequence Length | 349 aa |
1-acylglycerol-3-phosphate O-acyltransferase ABHD5
Review this target as Perilipin-1/ABHD5, mapped to UniProt Q8WTS1. ChEMBL maps the protein component as 1-acylglycerol-3-phosphate O-acyltransferase ABHD5. Sequence length is 349 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1565221 | 5.91 | IC50 | 1227.0 | Preclinical |
| CHEMBL17201 | 5.82 | IC50 | 1520.0 | Preclinical |
| CHEMBL60718 | 5.73 | IC50 | 1868.0 | Preclinical |
| CHEMBL1500987 | 5.68 | IC50 | 2068.0 | Preclinical |
| CHEMBL1535633 | 5.66 | IC50 | 2207.0 | Preclinical |
| CHEMBL1369296 | 5.64 | IC50 | 2278.0 | Preclinical |
| CHEMBL1414703 | 5.52 | IC50 | 2992.0 | Preclinical |
| CHEMBL1598561 | 5.5 | IC50 | 3170.0 | Preclinical |
| CHEMBL1363719 | 5.48 | IC50 | 3291.0 | Preclinical |
| CHEMBL1462108 | 5.48 | IC50 | 3339.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 1 | 44 | 5.2 |