Compound Detail
CHEMBL1565221
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Basic Information
| ChEMBL ID | CHEMBL1565221 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OCPXVDAZLOMXLU-WIXUPIFPSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
289.3
MW (Da)
3.90
ALogP
3
HBA
0
HBD
38.7
PSA (Ų)
0.63
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.95
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5/Perilipin-5 CHEMBL3885501 | IC50 | 5.95 | 5.95 | 1123.0 | 1 |
| Perilipin-1/ABHD5 CHEMBL3883313 | IC50 | 5.91 | 5.91 | 1227.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5/Perilipin-5 | IC50 | = | 1123.0 | nM | 5.95 | PUBCHEM_BIOASSAY: Luminescence-based biochemical high throughput dose response a... | - |
| Perilipin-1/ABHD5 | IC50 | = | 1227.0 | nM | 5.91 | PUBCHEM_BIOASSAY: Luminescence-based biochemical high throughput dose response a... | - |
Data from ChEMBL 36 via Core Engine