Compound Detail
CHEMBL150648
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Basic Information
| ChEMBL ID | CHEMBL150648 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GBZCFQFQXMJNSG-BQYQJAHWSA-N |
2
Targets
5
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
208.2
MW (Da)
3.64
ALogP
1
HBA
0
HBD
17.1
PSA (Ų)
0.48
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 5 meas. best 5.14
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.14 | 5.14 | 7244.4 | 1 |
| CG8425-PA [Drosophila melanogaster] CHEMBL4265 | IC50 | 4.1 | 4.1 | 79432.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 7244.36 | nM | 5.14 | Inhibition of juvenile hormone esterase | 14604674 |
| CG8425-PA [Drosophila melanogaster] | IC50 | = | 79432.82 | nM | 4.1 | In vitro inhibition of Trichoplusia Juvenile Hormone Esterase. | 12459025 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12459025 | 10.1021/jm020072w | No relevant target | 2 |
| 12459025 | 10.1021/jm020072w | Cocaine esterase | 1 |
| 12459025 | 10.1021/jm020072w | Acylcarnitine hydrolase | 1 |
| 12459025 | 10.1021/jm020072w | Liver carboxylesterase | 1 |
| 12459025 | 10.1021/jm020072w | CG8425-PA [Drosophila melanogaster] | 1 |
| 14604674 | 10.1016/j.bmc.2003.08.023 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine