Compound Detail
CHEMBL151400
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Basic Information
| ChEMBL ID | CHEMBL151400 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YWMGBZLHXVIJDF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
499.7
MW (Da)
7.24
ALogP
5
HBA
0
HBD
38.8
PSA (Ų)
0.23
QED
1
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Estrogen receptor CHEMBL2093866 | IC50 | 6.0 | 6.0 | 1000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Estrogen receptor | IC50 | = | 1000.0 | nM | 6.0 | In vitro inhibition of estrogen-stimulated MCF-7 cell proliferation | 10098655 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10098655 | 10.1016/s0960-894x(99)00050-5 | Estrogen receptor | 2 |
Data from ChEMBL 36 via Core Engine