Compound Detail
CHEMBL1517376
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Basic Information
| ChEMBL ID | CHEMBL1517376 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PBRIMTJJMFPCKV-UHFFFAOYSA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
281.3
MW (Da)
3.17
ALogP
3
HBA
0
HBD
46.6
PSA (Ų)
0.69
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.66
IC50 1 meas. best 5.67
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Guanyl-specific ribonuclease T1 CHEMBL1075043 | IC50 | 5.67 | 5.67 | 2133.0 | 1 |
| Ion channel NompC CHEMBL1293245 | EC50 | 4.66 | 4.66 | 22000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Guanyl-specific ribonuclease T1 | IC50 | = | 2133.0 | nM | 5.67 | PUBCHEM_BIOASSAY: Counterscreen for inhibitors of tRNA 2'-phosphotransferas... | - |
| Ion channel NompC | EC50 | = | 22000.0 | nM | 4.66 | PUBCHEM_BIOASSAY: Dose response cell-based high-throughput screening assay for a... | - |
Data from ChEMBL 36 via Core Engine