Compound Detail
CHEMBL154235
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL154235 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HJEPOXZLPHUVFE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
238.2
MW (Da)
0.90
ALogP
5
HBA
3
HBD
109.6
PSA (Ų)
0.72
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor ionotropic, kainate CHEMBL2094119 | IC50 | 4.07 | 4.07 | 85000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor ionotropic, kainate | IC50 | = | 85000.0 | nM | 4.07 | Compound tested for binding affinity towards Ionotropic glutamate receptor kaina... | 6325690 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 6325690 | 10.1021/jm00371a005 | Glutamate receptor ionotropic, kainate | 1 |
Data from ChEMBL 36 via Core Engine