Compound Detail
CHEMBL1549362
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1549362 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UFKXMTBPAONBSH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names
Molecular Properties
263.3
MW (Da)
4.28
ALogP
2
HBA
2
HBD
49.3
PSA (Ų)
0.74
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 4.48
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase CHEMBL4523429 | Kd | 4.48 | 4.48 | 32900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase | Kd | = | 32900.0 | nM | 4.48 | Binding affinity to recombinant hexa-histidine-tagged human full-length N-GLY1 c... | 27567076 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 27567076 | 10.1016/j.bmc.2016.08.019 | Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase | 2 |
| - | 10.6019/CHEMBL4296182 | Klebsiella pneumoniae | 1 |
| - | 10.6019/CHEMBL4296182 | Pseudomonas aeruginosa | 1 |
| - | 10.6019/CHEMBL4296182 | Candida albicans | 1 |
| - | 10.6019/CHEMBL4296182 | Staphylococcus aureus | 1 |
| - | 10.6019/CHEMBL4296182 | Acinetobacter baumannii | 1 |
| - | 10.6019/CHEMBL4296182 | Escherichia coli | 1 |
| - | 10.6019/CHEMBL4296182 | Cryptococcus neoformans | 1 |
Data from ChEMBL 36 via Core Engine