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Compound Detail

CHEMBL1551716

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C[C@@H]1O[C@@H](O[C@@H]2C=C3CCC4C(CC[C@]5(C)[C@@H](c6ccc(=O)oc6)CC[C@]45O)[C@@]3(C)CC2)[C@H](O)[C@H](O)[C@H]1O

Basic Information

ChEMBL ID CHEMBL1551716
Phase Preclinical
Structure Type MOL
InChI Key MYEJFUXQJGHEQK-BVLCKXLMSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

530.7
MW (Da)
3.01
ALogP
8
HBA
4
HBD
129.6
PSA (Ų)
0.44
QED
1
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C30H42O8
MW 530.66
Aromatic Rings 1
Heavy Atoms 38
NP-Likeness 2.73

Activity Summary

IC50 1 meas. best 5.78

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Jurkat
CHEMBL397
IC50 5.78 5.78 1660.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Jurkat IC50 = 1660.0 nM 5.78 PUBCHEM_BIOASSAY: Dose response confirmation of uHTS of chemical inhibitors of b... -

Literature References

PubMed DOI Target Context # Activities
- 10.6019/CHEMBL4651402 SARS-CoV-2 2

Data from ChEMBL 36 via Core Engine