Compound Detail
CHEMBL15527
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Basic Information
| ChEMBL ID | CHEMBL15527 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HUWDUVNMZCVTNR-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
249.3
MW (Da)
4.30
ALogP
2
HBA
0
HBD
22.1
PSA (Ų)
0.69
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Homo sapiens CHEMBL372 | IC50 | 5.7 | 5.57 | 2010.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Homo sapiens | IC50 | = | 2010.0 | nM | 5.7 | In vitro inhibitory activity on platelet aggregation induced by arachidonic acid... | 11212091 |
| Homo sapiens | IC50 | = | 3610.0 | nM | 5.44 | In vitro inhibitory activity of compound on platelet aggregation induced by coll... | 11212091 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11212091 | 10.1016/s0960-894x(00)00652-1 | Homo sapiens | 24 |
| 8387598 | 10.1021/jm00061a005 | A549 | 1 |
| 8387598 | 10.1021/jm00061a005 | HCT-8 | 1 |
| 8387598 | 10.1021/jm00061a005 | KB | 1 |
| 8387598 | 10.1021/jm00061a005 | P388 | 1 |
| 8387598 | 10.1021/jm00061a005 | L1210 (1565) | 1 |
Data from ChEMBL 36 via Core Engine