Compound Detail
CHEMBL1561148
PROSTAGLANDIN B1 Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1561148 |
| Name | PROSTAGLANDIN B1 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YBHMPNRDOVPQIN-VSOYFRJCSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
336.5
MW (Da)
4.57
ALogP
3
HBA
2
HBD
74.6
PSA (Ų)
0.48
QED
0
Ro5 Violations
13
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Solute carrier organic anion transporter family member 2A1 CHEMBL2073680 | Ki | 7.15 | 7.15 | 71.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Solute carrier organic anion transporter family member 2A1 | Ki | = | 71.2 | nM | 7.15 | TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cells | 8863817 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8863817 | - | Solute carrier organic anion transporter family member 2A1 | 1 |
| 23062825 | 10.1016/j.bmc.2012.09.040 | Acetylcholinesterase | 1 |
| 23062825 | 10.1016/j.bmc.2012.09.040 | Cholinesterase | 1 |
| 29043803 | 10.1021/acs.jnatprod.6b01052 | HL | 1 |
| 29043803 | 10.1021/acs.jnatprod.6b01052 | Chlamydia pneumoniae | 1 |
Data from ChEMBL 36 via Core Engine