Compound Detail
CHEMBL156381
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Basic Information
| ChEMBL ID | CHEMBL156381 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BBJFKWZNURQJNZ-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
277.4
MW (Da)
1.89
ALogP
4
HBA
0
HBD
30.9
PSA (Ų)
0.79
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rattus norvegicus CHEMBL376 | IC50 | 5.0 | 4.6 | 9924.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Rattus norvegicus | IC50 | = | 9924.0 | nM | 5.0 | Concentration of drug required to inhibit the stereospecific binding of [3H]-nal... | 6325691 |
| Rattus norvegicus | IC50 | = | 62531.0 | nM | 4.2 | Concentration of drug required to inhibit the stereospecific binding of [3H]nalo... | 6325691 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 6325691 | 10.1021/jm00371a012 | Rattus norvegicus | 5 |
| 6325691 | 10.1021/jm00371a012 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine