Compound Detail
CHEMBL1565295
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Cc1cc(NC(=O)CS(=O)(=O)c2cn(Cc3cccc(-c4ccn(C)n4)c3)c3ccccc23)no1
Basic Information
| ChEMBL ID | CHEMBL1565295 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SYUAMNRBIFTHNE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
489.6
MW (Da)
3.80
ALogP
8
HBA
1
HBD
112.0
PSA (Ų)
0.37
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.46
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M1 CHEMBL276 | EC50 | 5.46 | 5.46 | 3449.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | EC50 | = | 3449.0 | nM | 5.46 | PUBCHEM_BIOASSAY: Discovery of novel allosteric modulators of the M1 muscarinic ... | - |
Data from ChEMBL 36 via Core Engine