Compound Detail
CHEMBL1570732
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Basic Information
| ChEMBL ID | CHEMBL1570732 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SLSBTJGHGLHZFG-UHFFFAOYSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
331.2
MW (Da)
3.64
ALogP
6
HBA
0
HBD
81.8
PSA (Ų)
0.37
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 6.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tumor necrosis factor ligand superfamily member 10 CHEMBL5813 | IC50 | 6.17 | 6.13 | 683.0 | 2 |
| MDA-MB-435 CHEMBL614697 | IC50 | 5.52 | 5.52 | 2990.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tumor necrosis factor ligand superfamily member 10 | IC50 | = | 683.0 | nM | 6.17 | PUBCHEM_BIOASSAY: SAR analysis of compounds that potentiate TRAIL-induced apopto... | - |
| Tumor necrosis factor ligand superfamily member 10 | IC50 | = | 806.0 | nM | 6.09 | PUBCHEM_BIOASSAY: SAR analysis of compounds that potentiate TRAIL-induced apopto... | - |
| MDA-MB-435 | IC50 | = | 2990.0 | nM | 5.52 | PUBCHEM_BIOASSAY: SAR analysis of compounds cytotoxic to MDA-MB-435 cells. (Clas... | - |
Data from ChEMBL 36 via Core Engine