Compound Detail
CHEMBL1578657
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Basic Information
| ChEMBL ID | CHEMBL1578657 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OHJUYZMTGRBRQX-UHFFFAOYSA-N |
2
Targets
3
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
282.4
MW (Da)
2.46
ALogP
5
HBA
2
HBD
87.9
PSA (Ų)
0.90
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.09
EC50 1 meas. best 4.97
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.09 | 4.585 | 8120.0 | 2 |
| Probable global transcription activator SNF2L2 CHEMBL2362979 | EC50 | 4.97 | 4.97 | 10794.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 8120.0 | nM | 5.09 | PubChem BioAssay. Dry powder dose response confirmation of uHTS inhibitor hits ... | - |
| Probable global transcription activator SNF2L2 | EC50 | = | 10794.0 | nM | 4.97 | PubChem BioAssay. Luminescence-based cell-based high throughput dose response as... | - |
| Unchecked | IC50 | = | 82516.67 | nM | 4.08 | PubChem BioAssay. Dry powder dose response confirmation of uHTS inhibitor hits o... | - |
Data from ChEMBL 36 via Core Engine