Compound Detail
CHEMBL1585268
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Basic Information
| ChEMBL ID | CHEMBL1585268 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OIPWYTXPDHHORU-UHFFFAOYSA-N |
4
Targets
4
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
279.3
MW (Da)
2.40
ALogP
3
HBA
0
HBD
35.9
PSA (Ų)
0.74
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 4.44
IC50 2 meas. best 5.12
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Female germline-specific tumor suppressor gld-1 CHEMBL1293302 | IC50 | 5.12 | 5.12 | 7568.0 | 1 |
| Protein Rev CHEMBL1293282 | IC50 | 4.8 | 4.8 | 15785.0 | 1 |
| Kallikrein-7 CHEMBL2443 | EC50 | 4.44 | 4.44 | 36682.0 | 1 |
| Unchecked CHEMBL612545 | EC50 | 4.38 | 4.38 | 42046.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Female germline-specific tumor suppressor gld-1 | IC50 | = | 7568.0 | nM | 5.12 | PUBCHEM_BIOASSAY: Fluorescence polarization-based biochemical high throughput do... | - |
| Protein Rev | IC50 | = | 15785.0 | nM | 4.8 | PUBCHEM_BIOASSAY: Counterscreen for inhibitors of gld-1: Fluorescence polarizati... | - |
| Kallikrein-7 | EC50 | = | 36682.0 | nM | 4.44 | PubChem BioAssay. Fluorescence Intensity-based biochemical primary high throughp... | - |
| Unchecked | EC50 | = | 42046.0 | nM | 4.38 | PubChem BioAssay. Counterscreen for activators of kallikrein-7 (K7) zymogen: Flu... | - |
Data from ChEMBL 36 via Core Engine