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Compound Detail

CHEMBL1588014

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Cc1ccc(-n2cc(-c3ccccc3)c3c(N4CCOCC4)ncnc32)cc1

Basic Information

ChEMBL ID CHEMBL1588014
Phase Preclinical
Structure Type MOL
InChI Key YYMGFBJBNRLEOT-UHFFFAOYSA-N
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

370.5
MW (Da)
4.23
ALogP
5
HBA
0
HBD
43.2
PSA (Ų)
0.54
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C23H22N4O
MW 370.46
Aromatic Rings 4
Heavy Atoms 28
NP-Likeness -1.52

Activity Summary

IC50 3 meas. best 5.22

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 5.22 5.1367 5980.0 3

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine