Compound Detail
CHEMBL16050
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Basic Information
| ChEMBL ID | CHEMBL16050 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JNRVUYYOUJFYCM-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
316.3
MW (Da)
3.10
ALogP
6
HBA
3
HBD
91.6
PSA (Ų)
0.51
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Polymerase acidic protein CHEMBL1169598 | IC50 | 4.4 | 4.4 | 40000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Polymerase acidic protein | IC50 | = | 40000.0 | nM | 4.4 | Inhibitory concentration against cap-dependent endonuclease activity of influenz... | 12646026 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12646026 | 10.1021/jm020334u | Polymerase acidic protein | 2 |
| 12646026 | 10.1021/jm020334u | unidentified influenza virus | 1 |
Data from ChEMBL 36 via Core Engine