Compound Detail
CHEMBL160709
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Basic Information
| ChEMBL ID | CHEMBL160709 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | TXQKSMSLZVKQBI-FQEVSTJZSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
335.4
MW (Da)
4.31
ALogP
2
HBA
1
HBD
40.5
PSA (Ų)
0.86
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rattus norvegicus CHEMBL376 | IC50 | 5.72 | 5.72 | 1910.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Rattus norvegicus | IC50 | = | 1910.0 | nM | 5.72 | Inhibition of GABA uptake from rat diencephalon-midbrain, | 2985785 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2985785 | 10.1021/jm50001a020 | Rattus norvegicus | 2 |
Data from ChEMBL 36 via Core Engine