Compound Detail
CHEMBL16132
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Basic Information
| ChEMBL ID | CHEMBL16132 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ASDFUVTYTVOHPL-UHNVWZDZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
145.2
MW (Da)
-0.96
ALogP
3
HBA
3
HBD
69.6
PSA (Ų)
0.44
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| GABA-A receptor; anion channel CHEMBL1907607 | IC50 | 4.92 | 4.92 | 12000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| GABA-A receptor; anion channel | IC50 | = | 12000.0 | nM | 4.92 | Inhibition of [3H]GABA binding to Gamma-aminobutyric acid receptor of rat brain ... | 6292417 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 6292417 | 10.1021/jm00352a012 | No relevant target | 2 |
| 6292417 | 10.1021/jm00352a012 | GABA-A receptor; anion channel | 1 |
| 6292417 | 10.1021/jm00352a012 | GABA transporter | 1 |
Data from ChEMBL 36 via Core Engine