Compound Detail
CHEMBL1620412
DIETHAZINE 🧪 Phase II
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🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL1620412 |
| Name | DIETHAZINE |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | LURMIKVZJSMXQE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
2
Known Names
Molecular Properties
298.4
MW (Da)
4.63
ALogP
3
HBA
0
HBD
6.5
PSA (Ų)
0.79
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Activity Summary
IC50 1 meas. best 4.99
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Pleiotropic ABC efflux transporter of multiple drugs CHEMBL1697658 | IC50 | 4.99 | 4.99 | 10300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Pleiotropic ABC efflux transporter of multiple drugs | IC50 | = | 10300.0 | nM | 4.99 | Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae ... | 19188399 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19188399 | 10.1128/aac.00956-08 | Pleiotropic ABC efflux transporter of multiple drugs | 2 |
| 19188399 | 10.1128/aac.00956-08 | Snq2p | 1 |
| 19188399 | 10.1128/aac.00956-08 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine