Pleiotropic ABC efflux transporter of multiple drugs · SINGLE PROTEIN · Saccharomyces cerevisiae S288c
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As of 2026-09-13Protein identity stays anchored to UniProt P33302. Use UniProt P33302 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P33302 as the stable identity anchor, then attach disease evidence before program review.
Pleiotropic ABC efflux transporter of multiple drugs
Review this target as Pleiotropic ABC efflux transporter of multiple drugs, mapped to UniProt P33302. Sequence length is 1511 aa.
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This review treats Pleiotropic ABC efflux transporter of multiple drugs as ChEMBL target CHEMBL1697658, mapped to UniProt P33302. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Pleiotropic ABC efflux transporter of multiple drugs |
| Target Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae S288c |
| UniProt | P33302 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Pleiotropic ABC efflux transporter of multiple drugs |
| UniProt Accession | P33302 |
| Component Type | Protein |
| Sequence Length | 1511 aa |
Pleiotropic ABC efflux transporter of multiple drugs
Review this target as Pleiotropic ABC efflux transporter of multiple drugs, mapped to UniProt P33302. Sequence length is 1511 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1688548 | 6.16 | IC50 | 700.0 | Preclinical |
| CHEMBL1688549 | 5.89 | IC50 | 1300.0 | Preclinical |
| CHEMBL479 | 5.89 | IC50 | 1300.0 | Approved |
| CHEMBL422 | 5.85 | IC50 | 1400.0 | Approved |
| CHEMBL567 | 5.85 | IC50 | 1400.0 | Approved |
| CHEMBL726 | 5.77 | IC50 | 1700.0 | Approved |
| CHEMBL728 | 5.77 | IC50 | 1700.0 | Approved |
| CHEMBL1378 | 5.64 | IC50 | 2300.0 | Approved |
| CHEMBL1688550 | 5.51 | IC50 | 3100.0 | Preclinical |
| CHEMBL824 | 5.5 | IC50 | 3200.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 21 | 5.4 |
| single protein format | 1 | 0 | — |