Compound Detail
CHEMBL1628267
ETHYLPEROXYARTEMISITENE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1628267 |
| Name | ETHYLPEROXYARTEMISITENE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BENASNHJHCMGTI-SGEMFXFFSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
326.4
MW (Da)
3.08
ALogP
6
HBA
0
HBD
55.4
PSA (Ų)
0.45
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.94
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 4.94 | 4.94 | 11500.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | IC50 | = | 11500.0 | nM | 4.94 | Cytotoxicity against mouse Ehrlich Ascites carcinoma by trypan blue exclusion as... | 17618015 |
| NON-PROTEIN TARGET | IC50 | = | 11500.0 | nM | 4.94 | Cytotoxicity against mouse EAC after 3 days by MTT assay | 8350087 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17618015 | 10.1016/j.ejmech.2007.04.019 | NON-PROTEIN TARGET | 2 |
| 8350087 | 10.1021/np50096a007 | NON-PROTEIN TARGET | 2 |
Data from ChEMBL 36 via Core Engine