Compound Detail
CHEMBL1630381
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1630381 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YMULMPRRAPDSFG-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
528.5
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 8.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor delta CHEMBL3979 | EC50 | 8.21 | 8.21 | 6.2 | 1 |
| Peroxisome proliferator-activated receptor alpha CHEMBL239 | EC50 | 7.08 | 7.08 | 83.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor delta | EC50 | = | 6.2 | nM | 8.21 | Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cell... | 21074432 |
| Peroxisome proliferator-activated receptor alpha | EC50 | = | 83.1 | nM | 7.08 | Agonist activity at human PPAR-alpha expressed in african green monkey CV-1 cell... | 21074432 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21074432 | 10.1016/j.bmcl.2010.10.103 | Peroxisome proliferator-activated receptor alpha | 1 |
| 21074432 | 10.1016/j.bmcl.2010.10.103 | Peroxisome proliferator-activated receptor delta | 1 |
| 21074432 | 10.1016/j.bmcl.2010.10.103 | Peroxisome proliferator-activated receptor gamma | 1 |
Data from ChEMBL 36 via Core Engine