Compound Detail
CHEMBL1631121
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Basic Information
| ChEMBL ID | CHEMBL1631121 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WJEOVZCPVSJPQG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
304.4
MW (Da)
3.38
ALogP
1
HBA
2
HBD
44.9
PSA (Ų)
0.77
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 4.31
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Major prion protein CHEMBL3698 | Kd | 4.31 | 4.31 | 48600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Major prion protein | Kd | = | 48600.0 | nM | 4.31 | Binding affinity to mouse recombinant PrP (121-231) after 10 mins by surface pla... | 19015328 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19015328 | 10.1128/aac.01112-08 | Major prion protein | 2 |
Data from ChEMBL 36 via Core Engine