Compound Detail
CHEMBL1631494
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Basic Information
| ChEMBL ID | CHEMBL1631494 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DMJPZNSQIMFJNQ-JFBPSJKJSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
324.5
MW (Da)
1.11
ALogP
5
HBA
4
HBD
87.7
PSA (Ų)
0.57
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.2
IC50 1 meas.
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Nucleic Acid CHEMBL345 | EC50 | 4.2 | 4.2 | 63000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Nucleic Acid | EC50 | = | 63000.0 | nM | 4.2 | Binding affinity to RNA by RNA fluorescence assay | 21041083 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21041083 | 10.1016/j.bmcl.2010.10.001 | Nucleic Acid | 1 |
| 21041083 | 10.1016/j.bmcl.2010.10.001 | Bacterial 70S ribosome | 1 |
| 21041083 | 10.1016/j.bmcl.2010.10.001 | Ribosome | 1 |
Data from ChEMBL 36 via Core Engine